Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
Healthy Volunteers
NCT03981640

Neural Control of Kidney Blood Flow During Exercise in African American Adults

Led by University of Massachusetts, Boston · Updated on 2025-12-24

32

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

Sponsors

U

University of Massachusetts, Boston

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trials is to learn if healthy young African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are: * Do healthy young AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy young AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults? During two visits in the research lab, participants will: * Perform a fitness test * Perform cycling exercise while lying down * Undergo a cold hand test * Perform a mental math test Completing this clinical trial will help researchers to understand more about why many AA adults have heart and kidney problems, so future research can study ways to reduce the number of AA adults who have these health issues.

CONDITIONS

Official Title

Neural Control of Kidney Blood Flow During Exercise in African American Adults

Who Can Participate

Age: 18Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Self-report as either African American or White racial identity
  • Born in United States
  • Both biological parents identify as same racial identity as participant
  • Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)
  • Fluent in English
Not Eligible

You will not qualify if you...

  • Hispanic or Latino
  • Females who are pregnant or lactating
  • Cardiovascular or renal disease
  • Hypertension (blood pressure of more than or equal to 130/80 mmHg)
  • Diabetes
  • Obesity (body mass index of more than or equal to 30 kg/m2)
  • Smoker/Tobacco user
  • Acute medical conditions
  • Taking prescribed cardiovascular, antihypertensive, or renal medications

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Massachusetts Boston

Boston, Massachusetts, United States, 02125

Actively Recruiting

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Research Team

R

Rachel C Drew, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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