Actively Recruiting

Phase 2
Age: 18Years - 50Years
All Genders
NCT06609369

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Led by Yale University · Updated on 2025-06-13

114

Participants Needed

2

Research Sites

214 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.

CONDITIONS

Official Title

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Who Can Participate

Age: 18Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • English literate
  • Report heavy tobacco use including nicotine e-cigarettes for more than 6 months
  • Meet biochemical cutoff for recent cigarette smoking or e-cigarette use
  • Have an optimal body mass index
Not Eligible

You will not qualify if you...

  • Currently enrolled in other treatments
  • Have neuropsychiatric conditions that could interfere with participation or increase risks
  • Have medical contraindications for fMRI, varenicline, or behavioral treatment
  • Have causes of deficient sleep less likely to benefit from behavioral treatment
  • Women who are pregnant or nursing

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Connecticut Mental Health Center

New Haven, Connecticut, United States, 06519

Actively Recruiting

2

Yale University

New Haven, Connecticut, United States, 06520

Actively Recruiting

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Research Team

Y

Yu Chen, PhD

CONTACT

L

Lisa Fucito, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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