Actively Recruiting
Neural Mechanisms of Family-Focused Treatment for Youth Depression
Led by Boston University Charles River Campus · Updated on 2024-08-23
80
Participants Needed
2
Research Sites
166 weeks
Total Duration
On this page
Sponsors
B
Boston University Charles River Campus
Lead Sponsor
M
Massachusetts Institute of Technology
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused Treatment for Childhood-Depression (FFT-CD) outcomes. The main questions it aims to answer are: * What are differences between depressed and non-depressed participants on baseline neural and parenting indicators? * Do baseline neural and parenting indicators predict response to FFT-CD? * Does change in parenting and neural functioning mediate change in depression from baseline to follow-up? Participants will: * complete baseline clinical measures * complete neuroimaging tasks via Functional Magnetic Resonance Imaging (fMR) * undergo a 12-session course of FFT-CD * complete follow up evaluations and neuroimaging
CONDITIONS
Official Title
Neural Mechanisms of Family-Focused Treatment for Youth Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 7 to 12 years
- Child has a current diagnosis of major depressive disorder, persistent depressive disorder, or depressive disorder not otherwise specified, or no history of any mental health diagnosis
- Child lives with a parent or guardian willing to participate
- Child and parent able and willing to provide informed consent or assent
- Parent is not currently pregnant
- Parent can read and understand consent forms and provide consent for the child
- Parent is the biological parent or grandparent acting as parent and has lived with the child for more than 75% of the child's life
- Participants are proficient in English
- No disturbances like autism spectrum disorder, psychosis, current substance dependence, obsessive-compulsive disorder, or MRI contraindications that would interfere with participation
You will not qualify if you...
- Child has psychotic disorder, autism spectrum disorder, obsessive-compulsive disorder, active substance abuse or dependence, or intellectual disability
- Child has severe conduct disorders threatening home stability, including involvement with juvenile justice or children's protective services
- Child or primary caregivers do not speak English
- Child or parent has contraindications for neuroimaging such as claustrophobia, metal implants, braces, or certain electronic devices
- Child is currently taking antidepressant medication
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Boston University
Boston, Massachusetts, United States, 02215
Actively Recruiting
2
Athinoula A. Martinos Imaging Center at Massachusetts Institute of Technology
Charlestown, Massachusetts, United States, 02129
Actively Recruiting
Research Team
M
Martha C Tompson, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here