Actively Recruiting
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
Led by University of Utah · Updated on 2026-02-03
150
Participants Needed
2
Research Sites
239 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based therapy for patients with opioid-treated chronic low back pain.
CONDITIONS
Official Title
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 65 years
- Chronic low back pain lasting at least 6 months with pain on at least half the days
- Usual back pain rated 3 or higher on a 0-10 scale while on opioid medication
- Current use of prescription opioids for 3 months or more
You will not qualify if you...
- Prior experience with MBSR, MBCT, MORE, or extensive involvement in standardized meditation training
- Current cancer diagnosis
- Suicide intent or attempt within the past 30 days
- Psychosis or moderate to severe non-opioid substance use disorder in the past 6 months
- Presence of electronic or certain metal objects in the body incompatible with MRI
- History of abnormal brain MRI
- Unable to lie still on back for 1 to 1.5 hours
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of California, San Diego
La Jolla, California, United States, 92093
Actively Recruiting
2
Center on Mindfulness and Integrative Health Intervention Development
Salt Lake City, Utah, United States, 84108
Active, Not Recruiting
Research Team
E
Eric Garland, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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