Actively Recruiting
Neurobiological and Genomic Predictors of Relapse in Depression
Led by Mehmet Kemal Arikan · Updated on 2026-01-09
204
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to test whether the discontinuation of antidepressant medications for patients with depression can be decided after the normalization of biological parameters. The main questions it aims are: 1. When patients with depression treated with antidepressants, does their brain activity also become normal? If so, 2. Then, can we stop the antidepressant treatment and expect minimum repeat of depression? The participants who receive a specific antidepressant treatment will be asked to: * Undergo quantitative electroencephalography (qEEG), * Record Event-related potential (ERP), * Record Sleep EEG * Answer Hamilton Depression Rating Scale question their psychiatrists asked * Give blood sample for genetic analysis * Repeat the above mentioned procedures for at least 3 times during their treatment period. Researchers will compare the results of patients with the results of healthy controls.
CONDITIONS
Official Title
Neurobiological and Genomic Predictors of Relapse in Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Outpatients
- Diagnosed with Major Depressive Disorder according to DSM-5-TR
- Drug-free for at least 1 week
You will not qualify if you...
- Presence of any neurological or psychiatric comorbid conditions
- Hearing loss
- Physical diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Prof. Dr. Kemal Arıkan's Psychiatry Clinic
Istanbul, Turkey (Türkiye), 34380
Actively Recruiting
Research Team
M
Mehmet Kemal Arıkan, Prof.
CONTACT
R
Reyhan Ilhan, MSc.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here