Actively Recruiting
Neurobiological Markers of Treatment Response for Anxiety and OCD
Led by Haukeland University Hospital · Updated on 2022-12-23
500
Participants Needed
1
Research Sites
507 weeks
Total Duration
On this page
Sponsors
H
Haukeland University Hospital
Lead Sponsor
U
University of Oslo
Collaborating Sponsor
AI-Summary
What this Trial Is About
Obsessive-compulsive disorder (OCD) and anxiety disorders are common and debilitating conditions which are often chronic when treatment is not provided. International guidelines recommend cognitive behavioral therapy (CBT) as the first-line treatment, and research has shown that CBT can be delivered over a concentrated period of time. The Bergen 4-Day Treatment (B4DT) is an exposure-based treatment which is delivered over four consecutive days. B4DT has been shown to induce rapid and long-lasting remission in around 70% of patients. This provides a platform for studying psychological and neurobiological changes associated with treatment response and non-response. The present study will investigate longitudinal changes in psychological measures and DNA methylation in patients who receive the B4DT, as well as a subset will also undergo multimodal brain imaging.
CONDITIONS
Official Title
Neurobiological Markers of Treatment Response for Anxiety and OCD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with obsessive-compulsive disorder, panic disorder or social anxiety disorder using DSM-5 criteria
- Referred to National Clinic for 4-Day Treatment, Haukeland University Hospital, Bergen, Norway
- Consented to participate in the "Kvalitetsregister for konsentrerte behandlingsformat"
You will not qualify if you...
- Suicidal, ongoing mania, primary eating disorder, intellectual disability, ongoing psychosis, ongoing substance abuse
- For MRI substudy: MRI incompatibility such as pregnancy or metal implants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Bergen Center for Brain Plasticity
Bergen, Vestland, Norway, 5009
Actively Recruiting
Research Team
B
Bjarne Hansen, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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