Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT04566744

NeuroCognitive Bases of Tool Use

Led by Hospices Civils de Lyon · Updated on 2024-06-25

320

Participants Needed

1

Research Sites

317 weeks

Total Duration

On this page

Sponsors

H

Hospices Civils de Lyon

Lead Sponsor

U

Université Lumière Lyon 2

Collaborating Sponsor

AI-Summary

What this Trial Is About

Tool use is considered to be the hallmark of complex cognitive adaptations that humans have achieved trough evolution, that provides an adaptive advantage to the human species. Even if nonhuman species do use tools too, human tool use is much more complex and sophisticated. If humans have special abilities for tool use, it has to be grounded in a specific neuroanatomical substrate. Humans and nonhumans share a similar prehension system located within the superior parietal lobe and the intraparietal sulcus. However, there is a human specificity: the supramarginal gyrus within the left inferior parietal lobe is unique to humans, and could play a central role in tool use. This project aims to study the neurocognitive bases of human tool use with functional Magnetic Resonance Imaging (fMRI), to precise the cognitive mechanisms through which humans are able to use tools.

CONDITIONS

Official Title

NeuroCognitive Bases of Tool Use

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between the ages of 18 and 65 years old
  • Have given informed consent for the study
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding women
  • Persons under curatorship, deprived of civil rights, or deprived of their freedom
  • Not registered with the French Social Security System
  • Unable to read or write French
  • Known or newly diagnosed neurological or psychiatric illness
  • Use of psychoactive medications or recreational drugs on the day of the experiment
  • Noise intolerance
  • Unable to complete a questionnaire due to severe cognitive problems
  • Do not agree to inform their personal doctor if an MRI anomaly is found
  • Do not agree to be informed if an MRI anomaly is found
  • Presence of metallic or electronic implants or foreign metal objects in the body
  • Current or past employment as machinists, welders, or metal workers
  • Tattoos near the head or neck regions or permanent makeup
  • Unwilling to complete the study
  • Appearance of exclusion criteria during the study
  • Occurrence of an event preventing study completion
  • Excessive head movement during MRI (greater than 4mm)
  • Detection of artifacts in brain images collected

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

CERMEP

Bron, France

Actively Recruiting

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Research Team

F

François OSIURAK, PhD

CONTACT

Y

Yves ROSSETTI, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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