Actively Recruiting
NeuroControl of Nicotine Dependence
Led by University of Missouri-Columbia · Updated on 2024-10-01
30
Participants Needed
1
Research Sites
291 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the study is to examine the effects of continuous theta burst stimulation (cTBS) on different forms of cognitive control in adults who smoke cigarettes, and to determine if the location where cTBS is delivered may help smokers reduce or quit smoking. Participation in the study will take 3-weeks over 4 visits, with a total time commitment of approximately 12 hours.
CONDITIONS
Official Title
NeuroControl of Nicotine Dependence
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Nicotine dependence defined by smoking at least 8 cigarettes per day for 2 or more years, with expired carbon monoxide levels of 10 ppm or higher, positive urine cotinine test, and FTND score of 3 or more; or using electronic cigarettes 15 or more times per day for at least 1 year with positive urine cotinine test and PS-ECDI score of 3 or more
- Fluent in English
- Functional vision (corrective lenses allowed)
You will not qualify if you...
- Use of psychotropic or antiepileptic medications within the last month
- Presence of untreated illness or serious medical condition
- History of major neurological illness
- Contraindications to TMS or MRI, including history of neurological disorders, seizures, increased intracranial pressure, brain surgery, head trauma with loss of consciousness longer than 15 minutes, implanted electronic devices, or metal in the head
- Use of substances that lower seizure threshold
- Current or past psychosis
- Electroconvulsive therapy within the past 6 months
- Unstable cardiac disease, hypertension, severe kidney or liver insufficiency, or sleep apnea
- Blood alcohol concentration greater than 0.0
- Positive urine pregnancy test
- Any other condition that could affect participant safety, study compliance, or result interpretation as judged by the investigator
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Health Neuroscience Center
Columbia, Missouri, United States, 65203
Actively Recruiting
Research Team
B
Brett Froeliger, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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