Actively Recruiting
Neurofeedback Intervention for Reading Deficits in Subacute Stroke
Led by Kessler Foundation · Updated on 2026-05-08
28
Participants Needed
1
Research Sites
221 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel brain imaging technique, called real-time functional magnetic resonance imaging (fMRI) neurofeedback combined with right hand motor imagery, this project will re-instate brain activity in the left language-dominant hemisphere. Stroke patients will practice modulating their own brain activity using fMRI neurofeedback signal and will select the most effective mental strategies that help them maintain brain activation patterns associated with better reading recovery.
CONDITIONS
Official Title
Neurofeedback Intervention for Reading Deficits in Subacute Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First-ever left-hemisphere stroke less than 3 months prior to study recruitment or healthy volunteer
- Age between 18 and 80 years old
- Fluent and literate in English prior to stroke
- Reading deficits defined as more than 3 errors on the Paragraphs test of the Reading Comprehension Battery for Aphasia-2nd ed. (RCBA-2) consistent with healthy control accuracy criteria
You will not qualify if you...
- Unable to consent or complete study tasks
- Unable to undergo MRI (e.g., pregnancy, non-MRI compatible implants, claustrophobia)
- History of prior neurological disease such as brain tumor or Alzheimer's disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kessler Foundation
West Orange, New Jersey, United States, 07052
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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