Actively Recruiting
Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)
Led by NHS Greater Glasgow and Clyde · Updated on 2025-06-15
16
Participants Needed
1
Research Sites
135 weeks
Total Duration
On this page
Sponsors
N
NHS Greater Glasgow and Clyde
Lead Sponsor
U
University of Glasgow
Collaborating Sponsor
AI-Summary
What this Trial Is About
Rheumatoid arthritis is an autoimmune condition, causing inflammation and pain. Yet pain may persist even when inflammation has been treated. This residual pain, called nociplastic pain, has symptoms of a chronic pain condition called fibromyalgia. There are few effective therapies to address this residual pain. Published literature shows that fibromyalgia can be treated by neurofeedback, a noninvasive method that is based on the voluntary modulation of cortical activity. In this pilot study, the investigators want to test the effect of neurofeedback on the fibromyalgia component of pain in rheumatoid arthritis, and also to investigate its effects on related symptoms such as fatigue and sleep disturbance.
CONDITIONS
Official Title
Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fulfilment of the ACR/EULAR Classification Criteria for rheumatoid arthritis (RA)
- Fulfilment of the American College of Rheumatology criteria for chronic widespread pain
- Stable disease with swollen joint count 21 and CRP 210
- Normal or corrected to normal vision and hearing
- Right-handed
- Pain intensity of 4 or higher on the Visual Numerical Scale (0-10)
You will not qualify if you...
- Unable to understand the task
- Unable to provide written informed consent
- Unable to understand English
- Major neurological diseases such as Multiple Sclerosis, Stroke, Traumatic Brain Injury, Parkinson's Disease, or Alzheimer's Disease
- Medical or psychiatric conditions that would prevent study participation (e.g., psychosis, suicidal thoughts)
- Under active pain management with changing medications or non-drug treatments
- Participating in other interventional experimental studies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Clinical Research Facility (CRF), Queen Elizabeth University Hospital
Glasgow, Scotland, United Kingdom, G51 4LS
Actively Recruiting
Research Team
A
Aleksandra Vuckovic, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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