Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
All Genders
Healthy Volunteers
NCT07122739

Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

Led by Trustees of Princeton University · Updated on 2026-02-23

40

Participants Needed

1

Research Sites

150 weeks

Total Duration

On this page

Sponsors

T

Trustees of Princeton University

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.

CONDITIONS

Official Title

Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

Who Can Participate

Age: 18Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18-50
  • No history of psychiatric disorders or neurological disorders affecting the central nervous system
  • Not currently taking psychoactive medication or drugs of abuse
  • Eligible for MRI (no permanent metal or medical implants)
  • Normal color vision
  • Right-handed
  • Full reading and writing English comprehension
  • Must show spontaneous recovery behavior in a prescreening session
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Pregnancy (female participants)
  • Outside the age range of 18-50
  • History of psychiatric or neurological disease
  • Currently taking psychoactive medication or drugs of abuse
  • Color blindness
  • Left-handed
  • Less than full reading and writing English comprehension
  • Do not show spontaneous recovery behavior in a prescreening session
  • Refuse to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Princeton Neuroscience Institute

Princeton, New Jersey, United States, 08540

Actively Recruiting

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Research Team

A

Augustin C. Hennings, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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