Actively Recruiting
Neurofeedback From the Supplementary Motor Area for Tourette Syndrome
Led by Yale University · Updated on 2025-08-06
64
Participants Needed
1
Research Sites
220 weeks
Total Duration
On this page
Sponsors
Y
Yale University
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a clinical trial where adolescents aged 10-16 years old with Tourette Syndrome (or chronic tic disorder) are randomized to receive either real-time functional magnetic resonance imaging (fMRI) neurofeedback targeting the supplementary motor area (for the experimental intervention) or real-time fMRI neurofeedback (NF) from a control region (for the control intervention).
CONDITIONS
Official Title
Neurofeedback From the Supplementary Motor Area for Tourette Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Boys and girls, 10 to 16 years of age
- Current diagnosis of Tourette Syndrome or chronic tic disorder with active tics executable without head movement
- YGTSS score of at least 13 for Tourette Syndrome or at least 12 for chronic tic disorder
- Currently stable medication treatment with no planned changes during the study
- Family residence within 2 hours of Yale Medical Center and willingness to attend visits
- Ability of child and parents to speak and understand spoken English
- No metal medical implants or braces
- Not pregnant
- Body weight less than 250 lbs
- No claustrophobia
You will not qualify if you...
- Intelligence quotient below 80
- Current diagnosis of autism spectrum disorder, bipolar or psychotic disorder, or current suicidality
- Significant medical conditions such as heart disease, hypertension, liver or renal failure, pulmonary disease, or seizure disorder
- Psychotherapy initiated less than 8 weeks ago; ongoing psychotherapy started at least 8 weeks ago is allowed but no new psychotherapy during the study
- Exclusion if unable to localize target brain regions during first MR scan
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Yale University School of Medicine
New Haven, Connecticut, United States, 06520
Actively Recruiting
Research Team
C
Cheyenne Harris-Starling
CONTACT
J
Jitendra Awasti
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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