Actively Recruiting
Neuroimaging Reveals Treatment-related Changes in DLD
Led by University of Cincinnati · Updated on 2025-05-06
184
Participants Needed
6
Research Sites
266 weeks
Total Duration
On this page
Sponsors
U
University of Cincinnati
Lead Sponsor
C
Children's Hospital Medical Center, Cincinnati
Collaborating Sponsor
AI-Summary
What this Trial Is About
Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.
CONDITIONS
Official Title
Neuroimaging Reveals Treatment-related Changes in DLD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 48 to 71 months
- Average nonverbal intelligence quotient (IQ)
- Enrolled in a participating center
- Typically developing in receptive and expressive language, social skills, articulation, and other areas
- Diagnosed with developmental language disorder (DLD) affecting expressive grammar
- Normal oral motor function
- Typical social and pragmatic skills
- Average hearing thresholds
- Monolingual native speakers of Standard English
- No uncorrected vision problems
You will not qualify if you...
- Receiving any other speech-language or communication intervention
- Not safe for MRI scanning
- Placed in special education due to ability or behavior
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
New Horizon Childcare
Cincinati, Ohio, United States, 45207
Not Yet Recruiting
2
Empower Learn Create INC
Cincinnati, Ohio, United States, 45220
Actively Recruiting
3
Cincinnati Children's Hospital
Cincinnati, Ohio, United States, 45229
Not Yet Recruiting
4
CWFF CHild Development Center
Cincinnati, Ohio, United States, 45229
Actively Recruiting
5
Wesley Education Center for Children and Families
Cincinnati, Ohio, United States, 45229
Actively Recruiting
6
University of Cincinnati
Cincinnati, Ohio, United States, 45267
Actively Recruiting
Research Team
K
Karla N Washington, PhD
CONTACT
J
Jennifer J Vannest, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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