Study of Autologous Bone Marrow Stem Cell Treatment Given Intravenously and Intranasally for Neurologic Disorders

What this Trial Is About

Researchers are studying the use of autologous bone marrow derived stem cells BMSC to improve neurologic function in patients with various neurologic disorders and diseases. This study focuses on neurologic conditions that have caused functional damage unlikely to improve with current standard treatments. The trial aims to add to existing knowledge about the potential benefits of BMSC treatment, particularly using intravenous and intranasal delivery methods targeting the central nervous system. Participants receive treatment involving the collection of their own bone marrow stem cells, which are then separated and administered both intravenously and applied topically to the lower third of the nasal passages. This dual delivery approach is designed to help the stem cells reach areas of the brain via the bloodstream and along the trigeminal nerve pathways. The treatment is given as a single intervention with follow-up evaluations at multiple time points. During the study, participants will undergo neurological assessments at baseline and at 1, 3, 6, and 12 months after treatment to monitor changes in neurological function. Medical stability and ongoing safety will be evaluated by the participants primary care doctor and neurologists. The study will measure improvements in neurologic function and monitor any effects or risks related to the stem cell procedure over the course of one year following treatment.

Neurologic Stem Cell Treatment Study