Actively Recruiting
Neurolysis for the Treatment of Medial Chronic Knee Pain Due to Osteoarthritis
Led by FUSMobile Inc. · Updated on 2026-01-07
10
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study involves the use of sound waves to block pain signals caused by osteoarthritis of the knee. The sound waves are tightly focused on a specific area of the nerve. The sound waves cause a break in the nerve which carries pain signals. Sound waves transmit through the skin so there is no need for needles. The procedure takes approximately one hour. The device has been approved in Health Canada and Europe for the treatment of lower back pain. This study is to evaluate the use of the same device for people in Canada who have knee pain related to osteoarthritis.
CONDITIONS
Official Title
Neurolysis for the Treatment of Medial Chronic Knee Pain Due to Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Moderate to severe, predominantly medial chronic knee pain
- Age adult >18 years old
- WOMAC Score of 30 or higher
- Numerical Rating Score greater than 6 when walking
- Radiological confirmation of knee osteoarthritis (Kellgren-Lawrence Scale: 2-4)
- Skin to bone depth between 2 and 6 cm at the treatment area measured by ultrasound
You will not qualify if you...
- Previous surgery altering bone structure in the knee
- Severe pain in the other knee
- Unable to understand and complete study questionnaires in the official language
- Severe medical conditions preventing safe participation as determined by the study doctor
- Extensive scarring over the treatment area
- Enrolled or planning to enroll in another clinical trial during this study
- Active inflammatory arthritis (e.g., rheumatoid arthritis)
- Mental health disorders except compensated mood disorders
- Altered pain perception with high pain scores (NRS > 9, PCS > 30, SSS-8 > 11, CSI > 40)
- First-degree family member already enrolled in this study
- Scheduled for any interventional or surgical procedure within 3 months except minor surgeries
- Unable to attend follow-up visits or physiotherapy due to travel or other restrictions
- Chronic pain conditions like fibromyalgia or generalized osteoarthritis that affect symptoms
- Radiofrequency ablation of genicular nerves in the planned treatment limb within the past 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Unika Medical Centre
North York, Ontario, Canada, M3B3S6
Actively Recruiting
Research Team
M
Melissa Diep Research Coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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