Safety and Feasibility of Neurolyser XR Device Using Ultrasound to Treat Chronic Medial Knee Pain from Osteoarthritis

What this Trial Is About

Researchers are evaluating a new treatment using focused sound waves to block pain signals in people with knee pain caused by osteoarthritis. The study aims to test a device that has been approved for lower back pain but is now being studied for knee pain in Canada. This research focuses on safety and feasibility for people with chronic medial knee pain. The purpose is to see if the device can reduce pain by interrupting nerve signals without surgery or needles. The treatment involves using the Neurolyser XR device to deliver ultrasound waves targeted at the sensory nerves in the knee that cause pain. The procedure lasts about one hour and uses X-ray imaging to guide the device to the correct nerve area without any incisions. Participants will receive this non-invasive thermal ablation treatment once during the study. Some participants may also have an MRI between 5 and 7 days after treatment if possible. During the study, participants will have regular visits for physical exams and pain assessments using numerical rating scales, questionnaires, and medication history reviews. Researchers will measure pain reduction, safety, and changes in sensation at various times up to six months after treatment. They will also track procedure time, radiation exposure, and medication needs during the procedure. The study involves close monitoring to evaluate both pain relief and any treatment-related side effects.

Neurolysis for the Treatment of Medial Chronic Knee Pain Due to Osteoarthritis