Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT06601686

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1

Led by University of Wisconsin, Madison · Updated on 2025-11-12

12

Participants Needed

1

Research Sites

142 weeks

Total Duration

On this page

Sponsors

U

University of Wisconsin, Madison

Lead Sponsor

T

Tiny Blue Dot Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn whether brain stimulation technology can help people reach a meditative state quickly and easily without years of meditation training. The researchers want to see if this will help people distance themselves from their thoughts and feeling, and if this will lead to improvements in openness and wellbeing the same way meditation can. Participants will: * Complete questionnaires * Perform a guided meditation task (The Bell Task) * Wear a high density electrocochleography (hdEEG) cap * Undergo brain stimulation * Perform cognitive tasks

CONDITIONS

Official Title

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 80 years of any gender
  • Medically healthy individuals
  • English-speaking and able to provide consent and complete questionnaires
  • Healthy adults with a consistent meditation practice
  • Citizen or legal resident
Not Eligible

You will not qualify if you...

  • History of neurological disorders or brain injury including stroke or intracranial lesions
  • History of bipolar disorder, hypomania, or psychosis
  • Head trauma causing prolonged unconsciousness or more than 3 mild concussions
  • Poorly controlled headaches or migraines
  • Systemic illnesses or unstable medical conditions that increase seizure risk
  • History of seizures, epilepsy, abnormal EEG, or family history of treatment-resistant epilepsy except single benign seizures
  • Possible pregnancy (female participants of childbearing age must have a pregnancy test)
  • Presence of metal in the brain, skull, or head
  • Contraindications to MRI
  • Medical devices or implants like pacemakers, pumps, cochlear implants, vagal nerve stimulators, or dental implants unless approved
  • Substance abuse or dependence in past 6 months
  • Use of medications that affect seizure threshold
  • Claustrophobia
  • Back problems preventing lying flat for up to two hours
  • Motion sickness
  • Hair styles or coverings that cannot be removed or adjusted for MRI or stimulation sessions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Wisconsin

Madison, Wisconsin, United States, 53719

Actively Recruiting

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Research Team

S

Simone Bruno

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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