Actively Recruiting
Neuromodulation and Cognitive Training for Substance Use Disorders
Led by University of Minnesota · Updated on 2025-08-26
80
Participants Needed
1
Research Sites
267 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The relapsing nature of substance use disorder is a major obstacle to successful treatment. About 70% of those entering treatment will relapse within one year. To improve treatment outcome, new interventions targeting the underlying brain biomarkers of relapse vulnerability hold significant promise in reducing this critical public health problem. This study is testing a new intervention, namely tDCS-Augmented Cognitive Training, to engage these brain biomarkers to improve cognition and improve treatment outcomes.
CONDITIONS
Official Title
Neuromodulation and Cognitive Training for Substance Use Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Abstinent from any substance or alcohol use (excluding caffeine or nicotine) for a minimum of 3 weeks at study enrollment
- Has the intention to remain in their treatment program(s) until the end of the intervention portion of the study
- Able to provide written consent and comply with study procedures
- Meets the MINI 7 diagnostic criteria for either stimulant use disorder or alcohol use disorder
You will not qualify if you...
- Any medical condition or treatment with neurological effects such as stroke, tumor, or HIV
- Abstinent from substance use for more than 9 months
- Head injury causing loss of consciousness for more than 30 minutes
- Condition that would make study measures difficult or impossible to perform or interpret
- Age younger than 18 or older than 65
- Primary substance use disorder diagnosis other than stimulant or alcohol, except caffeine or nicotine
- Entered treatment program under a court mandate or legal incarceration
- History of electroconvulsive therapy or cortical energy exposure in the past 6 months, including other neuromodulation studies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Minnesota Fairview
Minneapolis, Minnesota, United States, 55454
Actively Recruiting
Research Team
M
Melanie Stimac
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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