Actively Recruiting
Neuromodulation of the Cortex and Spinal Cord
Led by Father Flanagan's Boys' Home · Updated on 2025-09-29
50
Participants Needed
1
Research Sites
289 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Specific Aim 1: To further quantify the difference in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence of persons with CP. Overall hypotheses: The sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be uncharacteristic in persons with CP when compared with neurotypical controls. Furthermore, the extent of the alterations in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be tightly linked with the clinical presentations of persons with CP. Specific Aim 2: To investigate the effect of transcutaneous current stimulation applied over the cortex and/or spinal cord on the sensorimotor cortical activity, spinal cord dynamics, and corticospinal coherence. Overall hypotheses: Compared with the sham controls, those receiving the transcutaneous current stimulation will demonstrate alterations in the strength of the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence. Moreover, the extent of the alterations in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be tightly linked with the clinical presentations of persons with CP.
CONDITIONS
Official Title
Neuromodulation of the Cortex and Spinal Cord
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Cerebral palsy participants with Gross Motor Function Classification (GMFCS) levels between I and IV
- Neurotypical controls with no known atypical neurodevelopment such as autism, Down Syndrome, or ADHD
- Age between 11 and 45 years
You will not qualify if you...
- Pregnancy
- Any condition considered by the investigator to contraindicate participation
- Presence of any ferrous metal implant or orthodonture interfering with MEG or MRI safety
- Orthopedic surgery within the last 6 months
- Metal in the body that precludes MRI use
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Boys Town National Research Hospital
Boys Town, Nebraska, United States, 68010
Actively Recruiting
Research Team
M
Max J Kurz, PhD
CONTACT
J
Jennifer M Kime, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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