Actively Recruiting
Neuromodulation Effect of Focused Ultrasound for Motor Recovery in Patients With Stroke
Led by National Taiwan University Hospital · Updated on 2026-04-13
50
Participants Needed
1
Research Sites
269 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Transcranial focused ultrasound (tFUS) can be used as a non-invasive brain neuromodulation technique. Low-intensity focused ultrasound has been demonstrated to be safe and have neuromodulatory effects on the cerebral cortex in healthy human and animal experiments.This study aims to investigate the effect of tFUS on cortical excitability for motor recovery in patients with stroke.
CONDITIONS
Official Title
Neuromodulation Effect of Focused Ultrasound for Motor Recovery in Patients With Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with stroke (hemorrhagic or ischemic) diagnosed by a certified physician
- Stroke occurrence within the past three months
- Upper limb muscle strength less than or equal to 4 on the Medical Research Council Muscle Testing scale
- No prior history of stroke, epilepsy, dementia, Parkinson's disease, or other neurodegenerative diseases
- Ability to maintain sitting posture for more than 15 minutes
- Age 18 years or older
You will not qualify if you...
- History of recurrent stroke, traumatic brain injury, brain tumors, spinal cord injury, Parkinson's disease, or musculoskeletal diseases affecting treatment
- Contraindications to focused ultrasound including pregnancy, cardiac pacemakers or implants, abnormal connective tissue diseases, or coagulopathy
- Inability to cooperate due to impaired consciousness, aphasia, or inability to consent
- Cranial bone factors preventing tFUS penetration
- Current anticoagulant use with coagulopathy
- Unsuitable for CT imaging examination
- Major physical illnesses or neurological disorders such as epilepsy or brain surgery
- Presence of metallic implants in the body
- Use of tricyclic antidepressants, analgesics, or antiepileptic drugs
- Sleep disorders during tFUS treatment
- History of alcoholism
- Severe or uncontrollable intracranial pressure
- Intracranial space-occupying lesions
- Significant calcification of intracranial vessels on CT imaging
- Lesions or wounds on the scalp in the target treatment area
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Taiwan University Hospital
Taipei, Taiwan
Actively Recruiting
Research Team
M
Meng Ting Lin, M.D.
CONTACT
M
Ming Yen Hsiao, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here