Actively Recruiting
Neuromodulatory Effects of Audio-proprio-phonatory Reinforcement Training on Subjective Tinnitus, Demonstrated by High-density Electroencephalogram (HD EEG)
Led by Centre Hospitalier Régional d'Orléans · Updated on 2025-12-30
56
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Our ecological approach to neuromodulation in the field of "acouphonology" empowers tinnitus patients to act as their own source of sound stimuli through audio-proprio-phonatory reinforcement (APPR). By engaging in self-phonations, individuals uncoverthe vast potential for sound production, which can effectively mask their tinnitus or induce residual inhibition, all without relying on external sources. This clinical study aims to illustrate the positive impact of audio-proprio-phonatory reinforcement training on individuals suffering from chronic subjective tinnitus. This will be further supported and quantified through high-definition electroencephalography (HD EEG) as we explore the relationship between changes in connectivity within specific brain regions and the varying degrees of response to the therapeutic protocol.
CONDITIONS
Official Title
Neuromodulatory Effects of Audio-proprio-phonatory Reinforcement Training on Subjective Tinnitus, Demonstrated by High-density Electroencephalogram (HD EEG)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Agreed to participate and provided consent
- Aged 18 years or older and younger than 85 years
- Have subjective tinnitus for more than 3 months
- Score of 38 or higher on the THI questionnaire at study start
- Own a smartphone compatible with the Siopi application and have computer internet access for videoconferences
- Completed the THI, VAS-D, and insomnia severity index questionnaires on the Siopi app
- Committed to following the study protocol, including independent training
- Agreed not to start any new tinnitus treatments during the study
- Able to understand and complete assessment instructions
You will not qualify if you...
- Suffering from objective tinnitus
- Currently using white noise generators
- Have consulted a phoniatrics specialist more than twice or participated in more than two sound therapy workshops
- Have bilateral hearing loss over 40 dB uncorrected or severe hearing loss with or without hearing aids
- Started a new therapy less than 2 months ago
- Have psychiatric disorders causing auditory hallucinations
- Under guardianship, curatorship, judicial protection, or deprived of liberty
- Not affiliated with a social security system
- Pregnant or breastfeeding
- Participating in another drug study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CHU Orleans
Orléans, France, 45067
Actively Recruiting
Research Team
I
Isabelle Dr MARIE-BAILLY, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here