Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07188350

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)

Led by Hospital Moinhos de Vento · Updated on 2026-03-25

150

Participants Needed

1

Research Sites

77 weeks

Total Duration

On this page

Sponsors

H

Hospital Moinhos de Vento

Lead Sponsor

F

Federal University of Health Science of Porto Alegre

Collaborating Sponsor

AI-Summary

What this Trial Is About

This clinical study aims to compare the effects of conventional physical therapy alone versus conventional physical therapy combined with neuromuscular electrical stimulation (NMES) in patients admitted to the ICU and undergoing invasive mechanical ventilation. Participants will be randomly assigned to receive either conventional physical therapy or the same therapy plus NMES applied to the lower limbs. The protocol includes muscle-specific stimulation parameters and safety criteria to postpone sessions in cases of clinical instability. The primary goal is to assess whether NMES improves muscle function and recovery in critically ill patients.

CONDITIONS

Official Title

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 18 years or older
  • Under invasive mechanical ventilation
  • Expected to require invasive mechanical ventilation for more than 48 hours
Not Eligible

You will not qualify if you...

  • Body mass index (BMI) of 35 kg/m² or higher
  • ICU stay longer than 7 ICU-free days or more than 3 continuous days of invasive mechanical ventilation before enrollment
  • Known intracranial conditions such as stroke or intracranial hypertension
  • Neuromuscular diseases like Guillain-Barré syndrome or myasthenia gravis at ICU admission
  • Inability to speak Portuguese or pre-existing cognitive impairment before ICU admission
  • Conditions preventing NMES treatment or muscle strength assessment in both legs (e.g., skin lesions, fractures, amputation)
  • Inability to transfer from bed to chair with or without assistance prior to hospital admission
  • Cardiac arrest causing ICU admission or occurring before screening
  • Deep vein thrombosis (DVT) or pulmonary embolism (PE) treated for less than 48 hours
  • Pregnancy
  • Known or suspected malignancy in the legs
  • Any care limitations including do-not-resuscitate orders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Moinhos de Vento

Porto Alegre, Rio Grande do Sul, Brazil, 90035-902

Actively Recruiting

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Research Team

L

Larissa Carolina Brandão da Cunha, MSc

CONTACT

C

Cassiano Teixeira, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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