Actively Recruiting
Neuronal Effects of Exercise in Schizophrenia
Led by University of Colorado, Denver · Updated on 2025-04-22
140
Participants Needed
1
Research Sites
578 weeks
Total Duration
On this page
Sponsors
U
University of Colorado, Denver
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study plans to learn more about how common drugs prescribed to individuals with schizophrenia contribute to weight gain, as well as how exercise and diet impact appetite and the brain's response to food. In this study, the investigators will be evaluating how participants' brains respond to food images as well as asking questions about their food preferences and intake and clinical symptoms. The investigators may also ask participants to complete an exercise or diet intervention to see how this changes brain responses or food preferences.
CONDITIONS
Official Title
Neuronal Effects of Exercise in Schizophrenia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of schizophrenia or schizoaffective disorder
- Age between 21 and 70 years
- Currently prescribed olanzapine, risperidone, clozapine, or haloperidol, OR not taking any neuroleptic medications
- Weight stable within 5 percent for the past 6 months
You will not qualify if you...
- Pregnancy
- Substance abuse
- Significant endocrine or metabolic diseases such as uncontrolled hypertension or severe hypertriglyceridemia
- MRI-specific exclusions such as claustrophobia or having metal in the body
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Colorado Anschutz Medical Campus
Aurora, Colorado, United States, 80045
Actively Recruiting
Research Team
K
Kristina T Legget, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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