Actively Recruiting

Age: 19Years +
All Genders
ID07057128

Descriptors of Neuropathic Pain and Its Association With Central Sensitization in Subacromial Pain Syndrome

Led by Izmir City Hospital · Updated on 2026-04-14

82

Participants Needed

1

Research Sites

9 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating the characteristics of neuropathic pain and its connection to central sensitization in people diagnosed with subacromial pain syndrome (SAPS), a condition involving shoulder pain lasting at least three months. This observational study will enroll 82 adults aged 19 years or older from a physical medicine and rehabilitation clinic. The study aims to understand how different pain descriptors, especially hyperalgesia, relate to neuropathic pain and central sensitization in SAPS patients. Participants will complete several validated questionnaires evaluating pain intensity using the Visual Analog Scale (VAS), neuropathic pain features with painDETECT, central sensitization with the Central Sensitization Inventory, and shoulder function through the Shoulder Pain and Disability Index (SPADI). A physical examination will measure the shoulder's range of motion using a goniometer. No imaging or invasive procedures will be performed during the study. Throughout the study, researchers will assess the presence of specific pain descriptors related to neuropathic pain and central sensitization patterns. They will analyze hyperalgesia at a single baseline assessment alongside other measures such as pain intensity, neuropathic pain, central sensitization, shoulder function, and range of motion. This information aims to improve understanding of pain mechanisms and support better clinical management for individuals with SAPS.

CONDITIONS

Brief Title

Neuropathic Characteristics of Subacromial Pain Syndrome

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of subacromial pain syndrome (SAPS)
  • Age 19 years or older
  • Shoulder pain lasting at least 3 months
  • Shoulder pain intensity of 3 or higher on the Visual Analog Scale in the past week
  • Positive result on Hawkins-Kennedy test
  • Positive result on Painful arc test
  • Positive result on Infraspinatus muscle strength test
Not Eligible

You will not qualify if you...

  • History of inflammatory disease involving the shoulder joint
  • History of neurological disorders
  • History of prior shoulder surgery
  • Positive drop arm test
  • Loss of passive range of motion in the shoulder joint
  • Presence of muscle strength loss
  • Structurally confirmed shoulder pathology based on imaging studies
  • Full-thickness tear of the rotator cuff muscles
  • Presence of neurodeficit in the upper extremity
  • Diagnosis of cancer or active infection
  • Use of medications for neuropathic pain within the past 3 months for any reason

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo assessments to measure pain intensity, neuropathic pain, central sensitization, function, and range of motion at baseline.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 3 years

Participants are observed without intervention to study the characteristics of subacromial pain syndrome over time.

Visits as scheduled for assessments

Trial Site Locations

Total: 1 location

1

İzmir City Hospital

Izmir, İzmir, Turkey (Türkiye), 35300

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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