Actively Recruiting
Neurophenotype Predicts CD Disease Progression
Led by First Affiliated Hospital, Sun Yat-Sen University · Updated on 2024-06-11
500
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is aimed to develop a novel multimodal neuroimaging-based model to characterize the neurophenotype of Crohn's Disease patients and assess its ability for predicting disease progression, using multiomics data to interpret the model. Participants will be followed-up of at least six months for patients without disease progression to assess the relationship between neurophenotype and intestinal outcomes.
CONDITIONS
Official Title
Neurophenotype Predicts CD Disease Progression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Crohn's Disease patients aged 18 to 45 years
- Completion of multimodal brain MRI and psychological questionnaires
- MR enterography, ileocolonoscopy, and blood or fecal samples collected within one week of brain MRI
- Follow-up of at least six months for patients without disease progression
- Right-handedness
You will not qualify if you...
- Use of antibiotics, probiotics, or prebiotics within three months prior to inclusion
- History of neurosurgery, cerebrovascular disease, or brain trauma
- Use of central nervous system drugs or antidepressants within three months prior to inclusion
- Identification of brain lesions on MR scan
- Claustrophobia
- Presence of metal implants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
XploreMET v3.0 system
Shanghai, China
Actively Recruiting
Research Team
X
Xuehua Li
CONTACT
R
Ruonan Zhang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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