Actively Recruiting
Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders
Led by University of Pennsylvania · Updated on 2026-03-11
100
Participants Needed
1
Research Sites
224 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The research study is being conducted to better understand parts of the human brain called the cortex, basal ganglia, thalamus, and cerebellum in patients with movement disorders (such as Parkinson's disease, essential tremor, dystonia, or ataxia). These brain structures are involved in movement disorders. This study attempts to better understand the brain electrical activity associated with these disorders, both in patients with and without deep brain stimulation (DBS). Recordings are made from the scalp with a noninvasive electrode and/or through the DBS stimulator if the participant has a stimulator model that is able to sense brain activity. These recordings are analyzed along with measures of movement disorder symptoms to identify brain signal signatures of symptoms.
CONDITIONS
Official Title
Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years of age and above
- Diagnosed by a movement disorders neurologist with Parkinson's disease
- Diagnosed by a movement disorders neurologist with dystonia
- Diagnosed by a movement disorders neurologist with tremor, including essential tremor
- Diagnosed by a movement disorders neurologist with cerebellar ataxia
- Diagnosed by a movement disorders neurologist with other hyperkinetic movement disorders such as chorea and tics
You will not qualify if you...
- Patients with dementia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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