Actively Recruiting
Neurophysiology of Reward Signaling in Parkinson's Disease
Led by Vanderbilt University Medical Center · Updated on 2026-02-13
75
Participants Needed
1
Research Sites
265 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to learn more about the brain activity underlying Parkinson's disease risk taking and reward seeking behaviors. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.
CONDITIONS
Official Title
Neurophysiology of Reward Signaling in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
- Planned clinical electrode trajectory that contacts caudate
- Age greater than or equal to 40
- Diagnosis of Parkinson's disease or other movement disorder
- Able to participate in intraoperative testing
- English speaking
You will not qualify if you...
- Age less than 40
- Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37212
Actively Recruiting
Research Team
I
Isabel Long, BS
CONTACT
S
Sarah Bick, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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