Actively Recruiting

Age: 18Years - 70Years
All Genders
NCT05277519

Neuroplasticity After Proprioceptive Rehabiliation

Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2026-03-09

56

Participants Needed

1

Research Sites

234 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the neuroplastic changes during and after instrumented proprioceptive rehabilitation relying on sequences of muscle vibration in subacute stroke stages.

CONDITIONS

Official Title

Neuroplasticity After Proprioceptive Rehabiliation

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hemiparesis at least transient in lower limb following an acquired brain injury (stroke or traumatic brain injury)
  • French spoken
  • Affiliated to a French social insurance
  • No previous traumatic, vascular or neurodegenerative injuries
  • Having presented during the acute phase or presenting a motor deficit of one of the lower limbs
  • Presenting an absence of autonomy of walking at the entrance of the rehabilitation department
  • In the sub-acute phase, i.e. from 15 days to 6 months after the accident
  • Presenting moderate cognitive disorders allowing them to understand instructions and give their consent
Not Eligible

You will not qualify if you...

  • Strong cognitive disorders
  • Maintenance of justice, tutelage, legal guardianship
  • Pregnancy and breastfeeding
  • Outpatients who do not have weekly follow-up in the rehabilitation department

AI-Screening

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Trial Site Locations

Total: 1 location

1

Pitié-Salpêtrière Hospital

Paris, France, 75013

Actively Recruiting

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Research Team

V

Veronique Marchand-Pauvert, PhD

CONTACT

E

Eleonore Bayen, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Neuroplasticity After Proprioceptive Rehabiliation | DecenTrialz