Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
Healthy Volunteers
NCT06688968

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

Led by University Hospital, Montpellier · Updated on 2025-03-19

120

Participants Needed

3

Research Sites

42 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Montpellier

Lead Sponsor

L

Laboratoire EPSYLON

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects. The main questions it aims to answer are: 1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects. 2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up. Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including : * A semi-structured interview to check the participants eligibility and gather demographic data. * Neuropsychological tests and questionnaires will then be administered. * A relative of the study participant will help complete questionnaires.

CONDITIONS

Official Title

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

Who Can Participate

Age: 60Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 60 years and older
  • French-speaking and volunteering for the study
  • Living at home with a relative
  • Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria
  • MMSE score greater than or equal to 20 for Alzheimer's disease
  • Diagnosis of idiopathic Parkinson's disease
  • MMSE score greater than or equal to 20 for Parkinson's disease
Not Eligible

You will not qualify if you...

  • No known neurological diseases such as epilepsy or other non-degenerative central nervous system diseases
  • No psychiatric disorders including chronic psychosis or psychotic episodes
  • No autistic disorders
  • No history of stroke or head trauma
  • No unstable medical conditions like cancer
  • Able to read and write
  • No hearing impairment without hearing aids
  • Provided informed consent
  • Able to give consent, not enrolled in emergency research
  • Affiliated with a social security scheme
  • Not deprived of liberty by legal or administrative decisions
  • Not under legal protection such as guardianship
  • Not participating in another research project with overlapping exclusion period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Montpellier Seniors' Association

Montpellier, Hérault, France, 34000

Not Yet Recruiting

2

CHU de Montpellier - CEPMo

Montpellier, Hérault, France, 34295

Actively Recruiting

3

CHU de Montpellier - CMRR

Montpellier, Hérault, France, 34295

Not Yet Recruiting

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Research Team

M

Mikaël Genguelou, PhD

CONTACT

K

KARIM BENNYS, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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