Actively Recruiting

Age: 3Years - 18Years
All Genders
Healthy Volunteers
NCT05913297

Neuroradiology Assesses Chiari Malformation's Impact on Airways, Cranial Base, and Sleep Disorders in Children.

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-02-27

138

Participants Needed

1

Research Sites

156 weeks

Total Duration

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AI-Summary

What this Trial Is About

The severity of sleep disorders in patients with Chiari malformations can vary. The investigators propose to establish a correlation between the severity of sleep-disordered breathing (SDB) and the quantitative neuroradiological data of the airways, cranial base foramina, and posterior cranial fossae

CONDITIONS

Official Title

Neuroradiology Assesses Chiari Malformation's Impact on Airways, Cranial Base, and Sleep Disorders in Children.

Who Can Participate

Age: 3Years - 18Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children (males or females) aged between 3 years and 18 years.
  • Clinical diagnosis of Chiari malformation 1 and 2.
  • Presence of informed consent for the initial clinical evaluation.
Not Eligible

You will not qualify if you...

  • Chiari Malformation I and II associated with neurological diseases or craniofacial malformations.
  • Cranial trauma or cardiac arrest.
  • Administration of centrally acting medications within 2 weeks prior to the study, except for antiepileptic treatment for patients who have had seizures.
  • Associated brain and cranial base tumors.
  • Refusal to sign the informed consent for the initial clinical evaluation.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fondazione Policlinico Gemelli IRCCS

Rome, Italy, Italy, 00168

Actively Recruiting

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Research Team

R

Rosalinda Calandrelli, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Neuroradiology Assesses Chiari Malformation's Impact on Airways, Cranial Base, and Sleep Disorders in Children. | DecenTrialz