Quantitative Neuroradiological Assessment of the Airways, Cranial Base Foramina, and Posterior Cranial Fossae in Children with Chiari Malformation Relationship with Sleep Disorders

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-02-27

138

Participants Needed

Research Sites

52 weeks

Total Duration

AI-Summary

What this Trial Is About

The severity of sleep disorders in patients with Chiari malformations can vary. The investigators propose to establish a correlation between the severity of sleep-disordered breathing (SDB) and the quantitative neuroradiological data of the airways, cranial base foramina, and posterior cranial fossae

CONDITIONS

Brief Title

Neuroradiology Assesses Chiari Malformation's Impact on Airways, Cranial Base, and Sleep Disorders in Children.

Who Can Participate

Age: 3Years - 18Years

All Genders

Healthy Volunteers

Eligibility Criteria

Inclusion Criteria:

Children (males or females) aged between 3 years and 18 years.
Clinical diagnosis of Chiari malformation 1 and 2.
Presence of informed consent for the initial clinical evaluation. The investigators commit to providing appropriate informational sheets to the parents of the patients (for those included in the study) during the initial clinical evaluation.

Exclusion Criteria:

Chiari Malformation I and II associated with neurological diseases or craniofacial malformations.
Cranial trauma or cardiac arrest.
Administration of centrally acting medications within 2 weeks prior to the study, except for antiepileptic treatment for patients who have had seizures.
Associated brain and cranial base tumors.
Refusal to sign the informed consent for the initial clinical evaluation. The investigators commit to providing appropriate informational sheets to the parents of the patients (for those included in the study) during the initial clinical evaluation.

Research Team

Rosalinda Calandrelli, MD

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Quantitative Neuroradiological Assessment of the Airways, Cranial Base Foramina, and Posterior Cranial Fossae in Children with Chiari Malformation Relationship with Sleep Disorders

On this page

AI-Summary

What this Trial Is About

Brief Title

Who Can Participate

Eligibility Criteria

Research Team

Not the Right Trial for You?

On this page

Who Can Participate

Eligibility Criteria