Actively Recruiting

Age: 18Years +
All Genders
NCT04733599

Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury

Led by Mayo Clinic · Updated on 2026-03-02

20

Participants Needed

2

Research Sites

304 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to see how much pain intensity is affected by high frequency spinal cord stimulation therapy in individuals with serious brachial plexus injury.

CONDITIONS

Official Title

Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years old
  • Neuropathic pain of the upper limb lasting 3 months or more after brachial plexus avulsion injury
  • Planned implantation of high-frequency spinal cord stimulation to treat chronic neuropathic pain from brachial plexus avulsion injury
Not Eligible

You will not qualify if you...

  • Pain that is non-neuropathic as shown by DN4 score less than 4
  • Pregnant at time of consideration for implant or planning pregnancy during study
  • Active substance use disorder of any kind
  • Current tobacco use
  • Use of moderate or high dose opioid medication (oral morphine equivalents >100 mg daily)
  • Active, untreated major psychiatric disorder that may interfere with participation
  • Involvement in active litigation related to injury
  • Has not undergone at least 3 months of conservative medical management including therapy and neuropathic pain medication trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Mayo Clinic

Jacksonville, Florida, United States, 32224

Actively Recruiting

2

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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