Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT05194566

Neurostimulation for the Treatment of Post-Stroke Aphasia

Led by QVITI S.A. · Updated on 2026-02-18

64

Participants Needed

2

Research Sites

168 weeks

Total Duration

On this page

Sponsors

Q

QVITI S.A.

Lead Sponsor

I

Icahn School of Medicine at Mount Sinai

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.

CONDITIONS

Official Title

Neurostimulation for the Treatment of Post-Stroke Aphasia

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Broca's or mixed aphasia by a Speech Language Pathologist
  • Left hemisphere brain injury from first ischemic or hemorrhagic stroke confirmed by CT/MRI
  • Chronic stage of stroke with time since stroke over 6 months
  • Naming Task accuracy between 10% and 60%
  • Age between 18 and 80 years
  • Right-handed before stroke
  • Ability to provide written informed consent
  • Fluent in English
Not Eligible

You will not qualify if you...

  • Severe cognitive, auditory, or visual impairment preventing cognitive and language testing
  • Presence of metal implants in the skull
  • Major untreated or unstable psychiatric disease
  • History of epilepsy or seizures
  • Use of medication that increases risk of epileptic seizures
  • Presence of cardiac stimulator, pacemaker, or vagus nerve stimulator
  • History of speech, language, hearing, or intellectual disability in childhood
  • Pregnancy
  • High intolerance to stimulation
  • Occurrence of epileptic seizure during trial
  • New neurological or mental symptoms during trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

Think & Speak Lab at Shirley Ryan AbilityLab

Chicago, Illinois, United States, 60611

Actively Recruiting

2

Abilities Research Center at Mount Sinai

New York, New York, United States, 10029

Actively Recruiting

Loading map...

Research Team

T

Tertia Jeppson

CONTACT

A

Aidan Rogers

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here