Actively Recruiting
Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
Led by Boston Children's Hospital · Updated on 2026-01-07
72
Participants Needed
1
Research Sites
330 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this research study we want to learn more about the character of neutrophils that are present in the blood of children with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Even though neutrophils are important in getting rid of germs, they also may be harmful to parts of the body by causing injury in organs in patients with sepsis. Neutrophils can change their character in sepsis. Because of this, it is important for doctors to know what kind of neutrophils are in the blood of children with sepsis so that they can work to develop therapies to prevent these cells from being harmful.
CONDITIONS
Official Title
Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients under 18 years old
- For sepsis group: patients meet the study's definition of sepsis
- For control group: patients under 18 scheduled for elective surgery requiring a preoperative blood draw or intravenous catheter placement
You will not qualify if you...
- Presence of congenital cardiac disease
- Use of chronic immunosuppressive drugs such as long-term corticosteroids
- Preexisting immunodeficiency diseases
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Boston Children's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
K
Koichi Yuki, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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