Actively Recruiting
A New Generation of Magnetoencephalographs for High Speed Functional Brain Imaging
Led by Hospices Civils de Lyon · Updated on 2025-07-15
80
Participants Needed
2
Research Sites
107 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal is to perform a first evaluation of the capabilities of a new generation of non-invasive magnetoencephalography whole head device using optically pumped magnetometers using Helium 4 as the sensitive element (OPM He4) to record brain magnetic activities. The investigators will record 1) healthy subjects stimulated with visual, auditory, somesthesic and motor stimuli and 2) athletes who suffered a mild concussion. The main hypothesis is that the OPM magnetoencephalographs (MEG) system will be able to detect brain activity. The secondary hypothesis is that the data recorded with the OPM MEG system will allow to reconstruct maps of the brain activity. To test the main hypothesis, they will compare the signal to noise ratio of brain activities between a classical MEG system and the new OPM He4 MEG. The secondary hypothesis will be tested through a comparison of the maps of brain activity obtained thanks to the data recorded with a classical MEG system and the new OPM He4 MEG.
CONDITIONS
Official Title
A New Generation of Magnetoencephalographs for High Speed Functional Brain Imaging
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 70 for healthy volunteers
- Strong motivation to participate in the study
- Signed informed consent for the study
- Male aged 18 to 40 for mild concussion participants
- Mild concussion confirmed by club doctor and neurologist within three weeks before the experiment
- Strong motivation to participate in the study
- Signed informed consent for the study
You will not qualify if you...
- Major cognitive deficit preventing understanding of instructions
- Previous neurological, psychiatric, or sleep disorders (except mild concussion for concussion group)
- Positive pregnancy test during inclusion
- Subjects under guardianship, curatorship, or judicial protection
- Subjects deprived of liberty
- Not affiliated to a social security system
- Contraindications to MEG and MRI including metal implants incompatible with examination (e.g., pacemaker, neurostimulator, cochlear implant, metallic prosthesis, intracerebral clip, implantable defibrillator, ventriculoperitoneal valve, dental appliance, ferromagnetic foreign body in upper body)
- Claustrophobia
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Service de Neurologie Fonctionnelle et d'Epileptologie, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon
Bron, France, 69677
Actively Recruiting
2
Centre Orthopédique Paul Santy
Lyon, France, 69008
Not Yet Recruiting
Research Team
J
Julien JUNG, MD
CONTACT
D
Denis SCHWARTZ
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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