Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT06903741

New Preservative-free Combination of Trehalose, Sodium Hyaluronate and N-acetyl-aspartyl-glutamate (NAAGA) in Dry Eye

Led by Laboratoires Thea · Updated on 2025-11-18

30

Participants Needed

1

Research Sites

31 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this prospective, non-randomized, non-comparative, monocentric PMCF study is to assess the performance of a new preservative-free combination of trehalose, sodium hyaluronate and NAAGA on DED at 6 months in 30 patients having dry eye disease. The main questions it aims to answer are: * To assess the performance and safety of T2769 at 3 months and 6 months. * To assess patient compliance to therapy. * To assess the occurrence of dry eye flares. Participants will be asked to use T2769 on a daily basis and complete a self-questionnaire throughout the study.

CONDITIONS

Official Title

New Preservative-free Combination of Trehalose, Sodium Hyaluronate and N-acetyl-aspartyl-glutamate (NAAGA) in Dry Eye

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged over 18 years
  • Able to give written informed consent prior the initiation of any procedure
  • History of dry eye syndrome for at least 3 months
  • Ocular Surface Disease Index (OSDI) score of 13 or higher
  • Never treated with artificial tears or no artificial tears used for at least 1 month before enrollment, or not satisfied with current artificial tears
Not Eligible

You will not qualify if you...

  • Known or suspected hypersensitivity to any component of the investigational medical device
  • History of or active systemic conditions that could interfere with study results or patient safety
  • Pregnant or breastfeeding women
  • Women of childbearing potential not surgically sterilized and not using effective contraception
  • Alcohol addiction or heavy smoking as judged by the investigator
  • Unable to understand study procedures or provide informed consent
  • Non-compliance with study requirements or unwillingness to complete self-questionnaires
  • Participation in another clinical study during this investigation
  • Participation in another clinical study within one month before this study
  • Institutionalized individuals due to legal or regulatory order, or inmates of psychiatric wards, prisons, or state institutions
  • Employees or family members of the study sites or sponsor
  • Previous, current, or anticipated use of prohibited treatments or treatment regimen changes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Group Practice Outpatient Clinic for Specialized Medical

Varna, Bulgaria, 9002

Actively Recruiting

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Research Team

M

Medical Affairs Director

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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