Actively Recruiting

Phase Not Applicable
Age: 70Years +
All Genders
NCT04452825

A New Psychotherapy Intervention for Older Cancer Patients

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-17

459

Participants Needed

1

Research Sites

330 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is being done to see if a new psychotherapy intervention called Cancer and Aging: Reflections for Elders (CARE) can effectively treat depression and distress in older cancer patients. CARE is a 5-session intervention that takes place over the phone. This study will compare CARE with the Social Work and Supportive Counseling (SWSC) intervention, which also takes place over the phone. SWSC is a standard psychotherapeutic intervention that has been shown to be a supportive and effective form of treatment for distress for patients with cancer. The researchers will look at which intervention is more effective in treating depression and distress in participants.

CONDITIONS

Official Title

A New Psychotherapy Intervention for Older Cancer Patients

Who Can Participate

Age: 70Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 70 years or older by self-report or medical record
  • Diagnosis of cancer by self-report or medical record
  • Currently receiving active treatment (radiation, chemotherapy, hormone), or received active treatment within past 6 months, or on active surveillance with follow-ups about every 6 months
  • Scored at least 6 on HADS Depression or Anxiety subscale, or at least 4 on the distress thermometer (not applicable for training participants)
  • Karnofsky Performance Rating Scale score of 60 or higher (not applicable for training participants)
  • Blessed Orientation-Memory-Concentration Scale score of 11 or less (not applicable for training participants)
  • Fluent in English, self-reported as "well" or "very well"
Not Eligible

You will not qualify if you...

  • Taking antidepressant medication for less than 3 months
  • Currently receiving hospice care
  • Unable to provide informed consent or complete study sessions and assessments
  • Current untreated major psychotic disorder (schizotypal personality disorder, schizophreniform disorder, schizoaffective disorder)
  • Patients with major psychiatric disorders will be reviewed by the study principal investigator before consent

AI-Screening

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Trial Site Locations

Total: 1 location

1

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

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Research Team

W

William Breitbart, MD

CONTACT

R

Rebecca Saracino, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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A New Psychotherapy Intervention for Older Cancer Patients | DecenTrialz