Actively Recruiting

Phase 4
Age: 18Years - 80Years
FEMALE
NCT05206500

NextGen - Clinical Implication of Next Generation Sequencing

Led by Wake Forest University Health Sciences · Updated on 2025-12-08

100

Participants Needed

1

Research Sites

341 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Recently more advanced techniques, including Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) are available to detect bacteria in urine based on bacterial genomes. Comparing to traditional culture, these techniques have more sensitivity and could potentially be of a great help in patients with Colony Count of less than 10,000 and more than zero.

CONDITIONS

Official Title

NextGen - Clinical Implication of Next Generation Sequencing

Who Can Participate

Age: 18Years - 80Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female at least 18 years of age
  • Urine culture growth of less than 10,000 Colony-Forming Units (CFU)
  • Understanding and acceptance of the need to return for all scheduled follow-up visits
  • Able to give informed consent
Not Eligible

You will not qualify if you...

  • Use of any catheter (Foley, suprapubic, or intermittent)
  • Inability to provide clean midstream urine sample
  • Antibiotic use within 2 weeks before consent
  • Pregnant or planning to conceive
  • Incarcerated

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wake Forest Health Sciences

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

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Research Team

M

Majid Mirzazadeh, MD

CONTACT

S

Sachin N Vyas, MS, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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NextGen - Clinical Implication of Next Generation Sequencing | DecenTrialz