Actively Recruiting

All Genders
NCT05673408

NIBP Validation Study

Led by Philips Clinical & Medical Affairs Global · Updated on 2025-12-09

189

Participants Needed

5

Research Sites

183 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to compare measurements of blood pressure (BP) between the Philips non-invasive blood pressure (NIBP) system (including NIBP cuff and portable patient monitor) and invasive radial for Subject Group 2 and 3, and radial or umbilical arterial line for neonates (A-line) in critical care patients.

CONDITIONS

Official Title

NIBP Validation Study

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient admitted into the NICU, PICU, ICU, or OR (operating room)
  • Adult aged 18 years and older, or parent/legal guardian of minor, willing and able to understand and provide informed consent/assent
  • Indication for NIBP cuff
  • Indication for radial arterial line for Subject Group 2 and Subject Group 3, and radial or umbilical arterial line for Subject Group 1
  • Meet stratification criteria across study groups including age and weight for neonates, sex distribution, limb circumference, and blood pressure ranges as specified in ISO 81060-2:2018/Amd-2:2024
Not Eligible

You will not qualify if you...

  • Inability to place the study device appropriately due to patient's anatomy or condition
  • Known pregnancy or lactating women (self-report)
  • Patients treated with an intra-aortic balloon pump
  • Aortic and mitral regurgitation (> 2nd degree)
  • Measurements taken in the lateral position
  • Currently participating in another clinical trial with any product, treatment and/or medication that clinically interferes with study endpoints
  • If valid SBP reference measurements for lateral difference is > 15 mmHg (except for neonates with umbilical A-line)
  • If valid DBP reference measurements for lateral difference is > 10 mmHg (except for neonates with umbilical A-line)
  • Subject does not qualify to participate at Principal Investigator's discretion for other reasons not mentioned above

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 5 locations

1

Mayo Clinic Jacksonville

Jacksonville, Florida, United States, 32224

Completed

2

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States, 27157

Not Yet Recruiting

3

Oregon Health & Science University

Portland, Oregon, United States, 97239

Not Yet Recruiting

4

University Health Women's and Children's Hospital

San Antonio, Texas, United States, 78229

Actively Recruiting

5

University of Utah

Salt Lake City, Utah, United States, 84112

Terminated

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Research Team

N

Natalie Hernandez, MBA

CONTACT

S

Shakun Karki

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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