Actively Recruiting

Phase 3
Age: 18Years - 70Years
All Genders
NCT07516769

Nicorandil as Anti-inflammatory in Rheumatoid Arthritis

Led by Tanta University · Updated on 2026-04-15

46

Participants Needed

1

Research Sites

125 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the possible efficacy and safety of nicorandil as anti-inflammatory in managing patients with active rheumatoid arthritis.

CONDITIONS

Official Title

Nicorandil as Anti-inflammatory in Rheumatoid Arthritis

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with active rheumatoid arthritis (not in remission) defined by a 28-joint disease activity score (DAS28) above 2.6
  • Patients receiving conventional disease-modifying antirheumatic drugs (DMARDs)
  • Adults aged 18 to 70 years
Not Eligible

You will not qualify if you...

  • Patients with heart disease including congestive heart failure, arrhythmia, or ischemic heart disease
  • Patients with diabetes or active infections
  • Patients with severe kidney or liver problems
  • Patients receiving biological DMARDs
  • Patients taking oral prednisolone over 15 mg per day
  • Patients allergic to the study medication
  • Patients using antioxidants
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tanta university

Tanta, Gharbia Governorate, Egypt

Actively Recruiting

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Research Team

K

Karim Abu Elfath Hussein

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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