Actively Recruiting
NIDCD Otolaryngology Clinical Protocol Biospecimen Bank
Led by National Institute on Deafness and Other Communication Disorders (NIDCD) · Updated on 2025-11-14
1000
Participants Needed
1
Research Sites
512 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Many disorders of the head and neck can affect a person s hearing; balance; smell; taste; swallowing; voice; or speech. These disorders include cancers and genetic and inflammatory diseases. To find better ways to diagnose and treat these disorders, researchers need to study tissues and other biological samples from people who have them. Objective: To collect biological samples for a repository that will be used for research. Eligibility: People of any age with a disorder of the head and neck that requires the taking of biological samples. The conditions may be any that affect hearing; balance; smell; taste; swallowing; voice; or speech. Design: Part 1: Participants will give permission for their leftover tissue samples to be used for research. These are tissue samples from the head and neck that were collected in the course of routine tests and care or other research studies. Information on each participant s age, diagnosis, and previous treatments will also be collected. Part 2: Some participants may be asked for more samples. All those aged 3 years or older will have a physical exam. They will provide blood and saliva samples. A cotton swab or brush will be used to collect cells from the inside of the cheek. Participants 18 years or older may have additional tests. They may provide nasal secretions: A piece of gelfoam or a sponge will be placed in the nose to soak up secretions for 5 to 10 minutes. They may have biopsies: Small samples of tissue will be cut from the skin and the tissue lining the mouth. Samples may be used for genetic testing.
CONDITIONS
Official Title
NIDCD Otolaryngology Clinical Protocol Biospecimen Bank
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to provide own consent or have a parent/guardian consent for minors
- Willingness and ability to sign informed consent
- Have a hearing, balance, smell, taste, voice, speech, or language condition under clinical care or research protocol
- Healthy volunteers aged 3 years or older enrolled on an approved research protocol
You will not qualify if you...
- Active symptomatic major organ disorders increasing biopsy risk, including bleeding disorders, ischemic heart disease, recent heart attack, active heart failure, or severe lung dysfunction
- Medical conditions like bleeding tendency that increase risk from biopsies or blood draws, determined by the principal investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
M
Maame S Akumatey
CONTACT
J
Joshua M Levy, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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