Biorepository Study for Head and Neck Disorders Affecting Hearing, Balance, Smell, Taste, Voice, and Speech Collecting Tissue and Biological Samples for Research

What this Trial Is About

Researchers are studying various disorders of the head and neck that may affect hearing, balance, smell, taste, swallowing, voice, or speech. These conditions include cancers, genetic, and inflammatory diseases. The study aims to collect biological samples to create a repository that will support research into better diagnosis and treatment methods for these disorders. Participants of all ages who have head and neck conditions may provide leftover tissue samples from routine care or other studies. Those aged 3 years and older may give blood, saliva, and cheek cell samples. Participants aged 18 and older might also provide nasal secretions and have small biopsies of skin and mouth tissue collected. These samples may be used for genetic and molecular research. During the study, researchers will collect clinical data such as age, diagnosis, and prior treatments. Physical exams will be performed for participants aged 3 and above. Samples and information will help create a biorepository that supports ongoing and future studies on normal and diseased tissues. This observational study continues over time and involves no investigational treatments, focusing on sample collection and data gathering.

NIDCD Otolaryngology Clinical Protocol Biospecimen Bank