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ID04106479

Monitoring Brain and Kidney Oxygen Levels Using Near-Infrared Spectroscopy in Newborns with Congenital Heart Defects and Comparing with Echocardiography during the First Week of Life

Led by McGill University Health Centre/Research Institute of the McGill University Health Centre · Updated on 2025-06-17

100

Participants Needed

1

Research Sites

139 weeks

Total Duration

AI-Summary

What this Trial Is About

This research focuses on newborns with congenital heart defects CHD, who face changes in blood flow and oxygen delivery during their first week of life. Researchers aim to compare near infrared spectroscopy NIRS, a noninvasive method that measures oxygen levels in the brain and kidneys using skin stickers, with echocardiography, which uses ultrasound to assess heart function and blood flow. The study seeks to understand how well NIRS correlates with traditional echocardiographic measures in babies with CHD. The study involves placing NIRS probes on the newborns forehead and abdomen to continuously monitor oxygen saturation in the brain and kidneys for up to seven days or until the baby is discharged or undergoes cardiac procedures. Daily echocardiography exams lasting 15 to 20 minutes will also be performed during this period. Newborns with CHD admitted to the neonatal intensive care unit NICU will be recruited either during fetal consultations or after birth. Participants will be closely monitored through continuous NIRS readings and daily echocardiography scans. Researchers will analyze correlations between cerebral and renal oxygen saturation and Doppler ultrasound measures of blood flow and heart performance throughout the first week of life. The study plans to enroll about 100 newborns to better understand how cardiac conditions affect oxygen delivery during this critical transitional period.

CONDITIONS

Brief Title

NIRS in Congenital Heart Defects - Correlation With Echocardiography

Research Team

G

Gabriel Altit, MD

J

Jennifer Gardner

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