Actively Recruiting

Age: 0Days - 7Days
All Genders
NCT04106479

NIRS in Congenital Heart Defects - Correlation With Echocardiography

Led by McGill University Health Centre/Research Institute of the McGill University Health Centre · Updated on 2025-06-17

100

Participants Needed

1

Research Sites

320 weeks

Total Duration

On this page

Sponsors

M

McGill University Health Centre/Research Institute of the McGill University Health Centre

Lead Sponsor

M

Medtronic

Collaborating Sponsor

AI-Summary

What this Trial Is About

Neonatal patients with congenital heart defects (CHD) have changing physiology in the context of transitional period. Patients with CHD are at risk of low perfusion status or abnormal pulmonary blood flow. Near infrared spectroscopy has been used in neonatal intensive care units (NICU) to measure end-organ perfusion. The investigator plan on monitoring newborns with CHD admitted to the NICU with NIRS and echocardiography during the first week of life and correlate measures of perfusion from Dopplers to cerebral and renal NIRS.

CONDITIONS

Official Title

NIRS in Congenital Heart Defects - Correlation With Echocardiography

Who Can Participate

Age: 0Days - 7Days
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Newborns with congenital heart defects such as tetralogy of Fallot, truncus arteriosus, D-transposition of great arteries, pulmonary stenosis, aortic stenosis, coarctation of the aorta, double inlet left ventricle, atrioventricular canal, double outlet right ventricle, hypoplastic left heart syndrome, tricuspid atresia, and pulmonary atresia with intact ventricular septum admitted to the NICU
  • Term infants admitted and monitored in the NICU with antenatal suspicion of coarctation of the aorta ruled out postnatally
  • Newborns admitted consecutively at the Montreal Children's Hospital NICU from January 2018 to January 2020
Not Eligible

You will not qualify if you...

  • Premature babies born before 34 weeks of estimated gestational age
  • Parents who do not consent to their baby's participation
  • Withdrawal of parental consent at any time during the study

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Mcgill University Health Centre

Montreal, Quebec, Canada, H4A 3J1

Actively Recruiting

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Research Team

G

Gabriel Altit, MD

CONTACT

J

Jennifer Gardner

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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