Actively Recruiting
Nissen Versus Dor Hiatal Hernia Repair
Led by Kuopio University Hospital · Updated on 2025-02-19
150
Participants Needed
1
Research Sites
259 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hiatal hernia can present with a wide range of symptoms. An usual surgical repair technique usually includes Nissen fundoplication, while other procedures are less frequently employed. However, recurrence and reoperation rates remain high. This randomized controlled trial aims to compare the efficacy of Nissen and Dor fundoplication in preventing hiatal hernia recurrence and reducing the risk of reoperation Participants undergoing minimally invasive hiatal hernia repair will be randomly assigned to either Nissen or Dor fundoplication. Postoperatively at 12 months, anatomical recurrence rates based on computed tomography scans and symptomatic recurrence rates, anti-reflux medication use, GERD-related quality of life, and dysphagia symptoms will be assessed. A subsequent long-term follow-up study will conducted afterwards utilizing national registry data to evaluate reoperation rates and anti-reflux medication use
CONDITIONS
Official Title
Nissen Versus Dor Hiatal Hernia Repair
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years of age
- Type II-IV hiatal hernia confirmed by radiology or endoscopy
- Scheduled for minimally invasive hiatal hernia repair
- Emergency minimally invasive surgery for hiatal hernia
- Informed consent obtained
You will not qualify if you...
- Recurrent hiatal hernia
- Need for esophageal lengthening procedure (Collis)
- Gangrene or need for any resection during emergency surgery
- Need for laparotomy or thoracotomy/thoracoscopy
- No written consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kuopio University Hospital
Kuopio, Finland, 70200
Actively Recruiting
Research Team
V
Ville Palomäki, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here