Actively Recruiting
Led by Al-Azhar University · Updated on 2025-04-03
50
Participants Needed
1
Research Sites
4 weeks
Total Duration
Researchers are evaluating the clinical effectiveness and safety of a 577 nm diode laser to treat non-inflammatory acne, specifically acne comedones. Acne vulgaris commonly affects adolescents and young adults, often causing scarring and lowered self-esteem. This study aims to explore laser treatment as an alternative to traditional topical and oral medications, which may have side effects or compliance challenges. The laser targets sebaceous glands and bacteria involved in acne development to reduce lesions. In this study, all patients receive sessions of the 577 nm diode laser treatment on one side of their face while the other side serves as an untreated control for comparison. The treatment focuses on reducing comedonal lesions without other interventions applied to the control side. This approach allows direct evaluation of the laser's effect within the same individual over time. Participants will be assessed clinically before and after treatment, with the main outcome being the reduction in the number of comedones measured over three months. Researchers will monitor safety and treatment responses during this period. The entire study involves adults aged 18 to 40 years who have at least 10 comedonal lesions on both sides of the face. This setup helps gather detailed information about the laser's potential in managing non-inflammatory acne.
CONDITIONS
577-nm Diode Laser in the Treatment of Non -Inflammatory Acne
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 months
Participants receive sessions of the 577 nm Diode laser treatment on one side of the face while the other side serves as a control without intervention.
Multiple treatment sessions over the course of the study
Duration - 3 months
Participants are assessed for reduction in the number of comedones through clinical evaluation before and after treatment.
1 to 2 visits for clinical assessment
Total: 1 location
1
Azhar Assuit university hospital
Asyut, Assuit, Egypt, 71511
Actively Recruiting
H
Hala Hasan Shehata, resident of dermatology
E
Essam El Din Mohamed Mohamed, Professor of Dermatology
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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