Actively Recruiting
NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome
Led by Fujian Medical University Union Hospital · Updated on 2024-07-08
180
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
At present, the diagnosis of Parkinsons disease(PD) mainly relies on clinical symptoms and is easily confused with atypical Parkinsonian syndrome(APS) in the early stages. There is an urgent need for reliable biomarkers. This project aims to use metabolomics technology based on proton nuclear magnetic resonance spectroscopy to study the metabolomic characteristics of patients with PD and APS, and preliminarily screen for possible diagnostic biomarkers of PD and APS.
CONDITIONS
Official Title
NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age range from 45 to 80 years old
- Diagnosis meeting Chinese expert consensus or International Society for Parkinson's Disease and Movement Disorders criteria for multiple system atrophy (MSA)
- MSA subtype classified as MSA-P (Parkinson's type) or MSA-C (cerebellar type)
- Diagnosis meeting Chinese or International Society for Parkinson's Disease and Movement Disorders criteria for progressive supranuclear palsy (PSP)
- Diagnosis of idiopathic Parkinson's disease meeting International Committee on Motor Disorders criteria (2015)
- Parkinson's disease subtype classified by MDS-UPDRS score into tremor predominant or PIGD type based on tremor to PIGD score ratio
You will not qualify if you...
- Hereditary Parkinson's syndrome or secondary Parkinson's syndrome
- History of deep brain stimulation (DBS) surgery
- History of malignant tumors
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fujian Medical University Union Hospital
Fuzhou, Fujian, China, 350000
Actively Recruiting
Research Team
Y
Ying Chen associate chief physician, Master
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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