Actively Recruiting

Age: 18Years +
All Genders
NCT07146698

No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study

Led by Benha University · Updated on 2025-09-11

60

Participants Needed

1

Research Sites

47 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.

CONDITIONS

Official Title

No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of both sexes aged 18 years or older
  • Invasive mechanical ventilation
  • Diagnosed with COPD (post-bronchodilator FEV1/FVC < 70) and followed through the outpatient clinic
  • Experiencing COPD exacerbation requiring ICU admission and invasive mechanical ventilation
  • Total of 60 patients divided into 2 equal groups
Not Eligible

You will not qualify if you...

  • Allergy to sedative medications used in the study
  • Kidney or liver impairment
  • Proven or suspected psychiatric or neurological impairment
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Benha University Hospitals

Banhā, Qalyubia Governorate, Egypt, 13518

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study | DecenTrialz