Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06356714

Nocardia Rubra Cell Wall Skeleton in Combination With Prior Second- or Third-line Regimens for the Treatment of Potentially Hazardous Colorectal Cancer SD Status

Led by Sun Jing · Updated on 2025-08-08

22

Participants Needed

1

Research Sites

132 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Evaluate the efficacy and safety of Nocardia rubra cell wall skeleton in combination with prior second- or third-line regimens for the treatment of potentially hazardous colorectal cancer SD(Stable Disease) status in the real world.

CONDITIONS

Official Title

Nocardia Rubra Cell Wall Skeleton in Combination With Prior Second- or Third-line Regimens for the Treatment of Potentially Hazardous Colorectal Cancer SD Status

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older, any gender
  • Diagnosed colorectal adenocarcinoma confirmed by pathology or cytology and imaging
  • At least one measurable lesion with longest diameter of 10 mm or more by spiral CT or 20 mm or more by conventional CT according to RECIST 1.1 criteria
  • Received prior second- or third-line therapy for advanced or metastatic colorectal cancer and have potentially hazardous stable disease status defined by specific tumor size and blood marker changes
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
  • Expected survival of 3 months or longer
  • Blood, liver, and kidney function tests within 7 days before screening meet specified thresholds for neutrophils, hemoglobin, platelets, bilirubin, gammaglutaminase, alkaline phosphatase, and creatinine
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Known allergic constitution
  • Having diabetes
  • Active severe infection
  • Other conditions considered exclusionary by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

the First Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210029

Actively Recruiting

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Research Team

J

Jing Sun

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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