Actively Recruiting
Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study
Led by Royal Marsden NHS Foundation Trust · Updated on 2023-06-15
500
Participants Needed
9
Research Sites
508 weeks
Total Duration
On this page
Sponsors
R
Royal Marsden NHS Foundation Trust
Lead Sponsor
R
Royal Brompton & Harefield NHS Foundation Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
NIMBLE is a prospective study for blood biomarker study of lung nodules alongside analysing data which has been collected routinely as part of patient care. The primary aim of NIMBLE is to assess whether artificial intelligence and machine learning based radiomics approaches can be used to distinguish between benign disease and malignancy in a new lung nodule after a previously treated cancer, and where malignant to differentiate between metastatic recurrence or a new primary lung cancer.
CONDITIONS
Official Title
Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients under active investigation or surveillance for incidental lung nodules
- Age over 18 years
You will not qualify if you...
- Active or previous diagnosis of malignancy within 5 years before the baseline scan
- Unable to give informed consent
- Active infection including tuberculosis or fungal infection
- Clinician-suspected or confirmed active or recent COVID-19 infection within 4 weeks before CT scan or blood sampling
AI-Screening
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Trial Site Locations
Total: 9 locations
1
Barking Havering and Redbridge University Hospitals NHS Trust
Goodmayes, Essex, United Kingdom, IG3 8YB
Actively Recruiting
2
Calderdale and Huddersfield NHS Foundation Trust
Huddersfield, United Kingdom, HD3 3EA
Actively Recruiting
3
Princess Alexandra Hospital
London, United Kingdom, CM20 1QX
Actively Recruiting
4
Whittington Health NHS Trust
London, United Kingdom, N19 5NF
Actively Recruiting
5
University College London Hospitals NHS Foundation Trust
London, United Kingdom, NW1 2BU
Actively Recruiting
6
Guy's and St Thomas' NHS Foundation Trust
London, United Kingdom, SE1 9RT
Actively Recruiting
7
Royal Marsden Hospital
London, United Kingdom, SW3 6JJ
Actively Recruiting
8
Northumbria NHS Foundation Trust
Newcastle upon Tyne, United Kingdom, NE27 0QJ
Actively Recruiting
9
Nottinghamshire Healthcare NHS Foundation Trust
Nottingham, United Kingdom, NG3 6AA
Actively Recruiting
Research Team
S
Sejal Jain
CONTACT
L
Laura Boddy
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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