Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
FEMALE
NCT04665882

Nomogram to Predict Breast Cancer Related Lymphedema

Led by Wuhan University · Updated on 2020-12-16

600

Participants Needed

1

Research Sites

368 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

It has been hypothesized that damaged arm lymphatic drainage is associated with the arm lymphedema after axillary lymph node dissection (ALND). However, the majority of breast cancer patients with complete ALND has not suffered from arm lymphedema, which appears to be due to the residual arm lymph nodes that has not been removed in the axillary dissection. With the compensation of the residual arm lymph flow above the level of axillary vein, the arm lymphatic drainage could keep balance and remain normal function. This arm lymphedema prediction model that included the protective factor, the proportion of arm lymph flow above the level of axillary vein, allows intraoperative intervention to be performed for the high-risk group. The arm lymphatics of these distinguished patients would be preserved to eliminate the occurrence of arm lymphedema in this study.

CONDITIONS

Official Title

Nomogram to Predict Breast Cancer Related Lymphedema

Who Can Participate

Age: 18Years - 80Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older with T1-3 invasive breast cancer
  • Clinically node-positive breast cancer confirmed by axillary palpation, ultrasound, and CT scan with contrast
  • Patients who had mastectomy with a positive sentinel lymph node
  • Patients who had breast-conserving surgery with more than two positive sentinel lymph nodes
Not Eligible

You will not qualify if you...

  • Received neoadjuvant chemotherapy
  • Previous history of breast cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zhongnan Hospital of Wuhan University

Wuhan, Hubei, China, 430071

Actively Recruiting

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Research Team

Q

Qianqian Yuan, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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