Actively Recruiting
Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals
Led by Steno Diabetes Center Copenhagen · Updated on 2026-05-04
8
Participants Needed
2
Research Sites
47 weeks
Total Duration
On this page
Sponsors
S
Steno Diabetes Center Copenhagen
Lead Sponsor
A
Aarhus University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The investigators will conduct a proof-of-principle 4-weeks low-calorie diet (LCD) intervention study in low birth weight (LBW) subjects and normal birth weight (NBW) controls with documented (MR scan) liver fat content equal to or above 5%. The investigators will provide extended in-depth mechanistic insight into the role of impaired subcutaneous adipose tissue (SAT) expandability in ectopic fat deposition before and after LCD.
CONDITIONS
Official Title
Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects with NAFLD (liver fat content 5% verified by MR scan in screening)
You will not qualify if you...
- BMI less than 18.5 or greater than 30 kg/m2
- Family history of diabetes (siblings, parents, grandparents)
- Diseases or medications affecting the primary outcome
- Self-reported high physical activity level
- Alcohol intake above general recommendations
- Metabolic or liver disease
- Weight gain or loss of more than 3 kg within the past 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Steno Diabetes Center Aarhus
Aarhus, Denmark
Actively Recruiting
2
Steno Diabetes Center Copenhagen
Herlev, Denmark
Actively Recruiting
Research Team
C
Charlotte Brøns, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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