Actively Recruiting
Non-Helium Magnetoencephalography in Pediatric Refractory Epilepsy
Led by Guangzhou Women and Children's Medical Center · Updated on 2025-07-14
100
Participants Needed
1
Research Sites
164 weeks
Total Duration
On this page
Sponsors
G
Guangzhou Women and Children's Medical Center
Lead Sponsor
B
Beijing X-Magtech Technology Limited
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to evaluate the effectiveness of Magnetoencephalography (MEG) in the preoperative assessment of children with refractory epilepsy, particularly in identifying the seizure focus, and to compare it with the gold standard methods of Stereo-electroencephalography (SEEG) and Electrocorticography (ECoG). The main questions this study aims to answer are: 1. How consistent is MEG with SEEG/ECoG in locating the epileptic focus in children with refractory epilepsy? 2. What is the clinical efficacy of MEG in identifying epileptic foci? Participants will: 1. Be divided into 2 groups: the case group and the control group. Participants in the case group will undergo both MEG and SEEG/ECoG for preoperative assessment, while patients in the control group will undergo only SEEG/ECoG before surgery. 2. Be followed up at 1, 3, 6, and 12 months after surgery to assess seizure control, neurological function, and quality of life.
CONDITIONS
Official Title
Non-Helium Magnetoencephalography in Pediatric Refractory Epilepsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 3 and 18 years old
- Diagnosed with refractory epilepsy
- Able to cooperate with magnetoencephalography evaluation and recording
You will not qualify if you...
- Serious comorbidities or neurological or psychiatric disorders affecting magnetoencephalography
- Use of drugs that affect central nervous system function
- Not suitable for surgical procedures
- Progressive neurological disorders
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Guangzhou Women and Children's medical center
Guangzhou, Guangdong, China, 511399
Actively Recruiting
Research Team
Y
Ye Song, Medical Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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