Actively Recruiting
A Non-interventional Registry for Patients with Hepatitis B Virus Infection
Led by Hannover Medical School · Updated on 2025-03-13
3000
Participants Needed
1
Research Sites
238 weeks
Total Duration
On this page
Sponsors
H
Hannover Medical School
Lead Sponsor
E
European Union
Collaborating Sponsor
AI-Summary
What this Trial Is About
In order to tackle the unmet needs in chronic HBV infection, a consortium of clinical partners has gathered to establish a registry for patients with hepatitis B mono- and co-infections. The partners will build up a European-wide registry to be able to stratify patients for upcoming clinical trials. Extensive analyses of virus and host-specific parameters are to be carried out from these patients. The knowledge gained thereby should contribute to a better understanding of the HBV control and enable patient stratification with regard to immunomodulatory therapies. Furthermore, hepatitis B patients are to be identified who are willing to participate in future studies to investigate immunotherapies to cure HBV infections (e.g. therapeutic vaccines).
CONDITIONS
Official Title
A Non-interventional Registry for Patients with Hepatitis B Virus Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Hepatitis B Virus infection
- For TherVacB sub-cohort: confirmed chronic hepatitis B with HBsAg positive for at least 1 year before joining
- For TherVacB sub-cohort: documented HBeAg status for at least 6 months
You will not qualify if you...
- For TherVacB sub-cohort: age over 70 years
- Co-infection with HIV or hepatitis C virus (RNA positive)
- Clinically relevant liver diseases such as ALD, NASH, Haemochromatosis, Autoimmune hepatitis, AT1, Wilson's disease, primary biliary cirrhosis
- Significant other illnesses like cancers
- Receiving immunosuppressive treatment greater than 40 mg Cortisol-equivalent
- Liver cirrhosis diagnosed clinically or by imaging
- History of hepatocellular carcinoma
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hannover Medical School
Hanover, Germany, 30625
Actively Recruiting
Research Team
P
Petra Dörge
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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